Is Your Birth Control Shot Putting You at Risk? Uncovering the Truth
In a world where contraceptive choices seem endless, injectable birth control has emerged as a popular option for many women. But what’s the truth behind these convenient shots?

Image by Diana Polekhina / Unsplash
You may wonder about their safety and side effects. Recent research and emerging medical insights reveal a complex web of potential health considerations that demand your attention.
But fear not. This blog post will explain how these injections work and what risks you may face. You will also learn about the potential legal and research developments.
Understanding Depo-Provera
Depo-Provera is an injectable contraceptive containing synthetic progestin. It is also dubbed the “shot” or DMPA contraceptive injection. It was authorized for contraceptive use by the U.S. Food and Drug Administration (FDA) in 1992.
The shot emits the hormone depot-medroxyprogesterone acetate (DMPA), a progestin that inhibits ovulation and tightens cervical mucus. This makes it difficult for sperm to reach an egg. It can be delivered in two ways:
Injected into large muscles like the shoulders or glutes (Depo-Provera and generic alternatives)
Injected into the skin of the stomach or thigh (Depo-SubQ Provera 104).
The former uses 150 mg of progestin as a dose and can only be administered by healthcare providers. The latter contains 104 mg progestin and can be self-administered. According to a KFF fact sheet, you’ll need a dose every 12 weeks or 3 months. When you strictly stick to this schedule, the shot is 96% effective. Once you stop the shot, your body will require around 10 months till it can get pregnant.
This has made it a hit among younger, black, and low-income making women, as it doesn’t require constant attention. Hence, the global injectable contraceptive industry is booming. Global Market Insights reveals the market was valued at $339.5 million in 2022. They expect it to surpass $477 million in 2032.
Similarly, the North American industry generated over $137 million in revenue. Estimations suggest the region will contribute nearly $187 million in revenue by 2032.
Assessing Potential Risks and Side Effects
You might face side effects when using the injection. Weight gain, menstrual cycle changes, stomach pain, discomfort, decreased libido, headaches, irregular bleeding, and nervousness are some typical side effects.
These effects subside within two to three months as the body adapts to the hormonal shifts. However, it varies for each individual. The shot also has some serious side effects. According to Drugwatch, it features an FDA black box warning, the most severe label warning. It warns of reduced bone density, increased likelihood of breast cancer, and allergic breakouts.
Furthermore, bone loss will increase with wider usage duration and is irreversible. Similarly, it shouldn’t be used for more than 2 years unless there are no adequate birth control alternatives. Other serious ill effects include blood clotting, ectopic pregnancy, and the risk of high blood sugar in diabetic patients.
Healthcare providers advise monitoring for such changes. Remember, not all effects are obvious. You may experience symptoms that need medical follow-up. Health experts stress the need for careful review if you have pre-existing conditions.
Legal Controversies and Consumer Advocacy
Concerns over side effects have led to legal actions. A 2024 study published in the British Medical Journal reveals using shots can increase the risk of certain brain tumors. The research notes that Depo-Provera users are 555% more likely to develop meningiomas than non-users.
The Depo-Provera lawsuit has brought these issues to the forefront, revealing potential risks beyond typical side effect warnings. Depo-Provera’s manufacturer, Pfizer, is drawing flak as people wonder whether it reported these side effects. The company’s decision to omit the meningioma warning label, which is present on European labels, has further raised scrutiny.
TruLaw reveals the Judicial Panel on Multidistrict Litigation (JPML) consented to create an MDL in January 2025. However, the location of the centralized proceedings isn’t finalized, as the plaintiffs lobby for California while Pfizer pushes for New York. Once the panel determines the court, all federal lawsuits will be shipped to that district for pretrial hearings.
Similarly, News.com.au reports Australian lawyers calling on shot users to sign on for a potential lawsuit. They are still investigating whether injections can cause brain tumors. The injections have been available in Australia since 1972, and as of December 2024, over 24,000 million Aussie women use them.
Understanding Your Contraceptive Journey
Not all contraceptive methods work the same for everyone. What resonates with one woman may not be ideal for another. Consider these factors when evaluating injectable contraceptives:
Your overall health history
Potential side effects
Long-term reproductive goals
Individual hormonal responses
Alternative options exist. Consulting with a healthcare professional can help you find the most suitable contraceptive method tailored to your unique needs.
Commonly Asked Questions
Q1. Are there any non-hormonal birth control alternatives to Depo-Provera?
Yes, several non-hormonal options exist! These include copper IUDs, which prevent fertilization via copper's spermicidal effect. Barrier techniques like condoms and diaphragms shut out the sperm. Fertility awareness methods track ovulation for natural family planning. Discuss these with your doctor to see if they suit your lifestyle and health.
Q2. What should you ask your doctor before starting injectable birth control?
Ask about how the injection may interact with your health history and pre-existing conditions. Inquire about expected side effects, available alternatives, and the monitoring process. This conversation helps ensure the method fits your lifestyle and you feel confident in your decision.
Q3. Can I get the Depo-Provera shot while breastfeeding?
It is deemed safe for use when breastfeeding. It doesn't typically affect milk production or infant health. Experts recommend using it after 6 months post-pregnancy. However, it's always best to discuss this with your doctor to weigh the benefits and any potential, albeit small, risks.
Your health journey is personal and unique. Injectable contraceptives offer convenience, but they're not a one-size-fits-all solution. Understanding potential risks, staying informed, and maintaining open communication with your healthcare provider is essential in managing your reproductive health.
Remember, you're not alone in navigating these complex choices. Every woman's health journey is different, and there's no shame in seeking comprehensive information and professional guidance.